Glucosamine Forms the basic building blocks of larger molecules in joint tissue. It directly stimulates cartilage cells and increases their production of Hyaluronic acid, which is important for synovial fluid to have its lubricating effect in the joint - MSM Natural anti-inflammatory - Chondroitin Sulphate Anti-inflammatory properties, as well as prohibiting degeneration of cartilage Is of low molecular weight to increase its absorptionDoes not contain shark cartilage. (Shark cartilage is high molecular weight which prohibits its absorption)